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spss statistical software version 23.0  (SYSTAT)


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    SYSTAT spss statistical software version 23.0
    Spss Statistical Software Version 23.0, supplied by SYSTAT, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/spss+statistical+software+version+23%2E0/spss+statistical+software+version+23+0/10__1016_slash_j__jddst__2023__104715-137-1-6
    Average 90 stars, based on 1 article reviews
    spss statistical software version 23.0 - by Bioz Stars, 2026-09
    90/100 stars

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    Software:

    Article Title: Integrated in vitro – In vivo – In silico studies in the pharmaceutical development of propranolol hydrochloride mucoadhesive buccal films
    Article Snippet: In order to exploit the advantage of drug delivery through the buccal mucosa, mucoadhesive buccal films with propranolol hydrochloride based on polyethylene oxide, hydroxypropyl methylcellulose, and polyvinyl alcohol have been developed.. The aim of this study was the development, pharmaceutical-technological (uniformity of mass and drug content, film thickness, potential interactions between polymers and propranolol hydrochloride, in vitro drug permeation and drug release, mechanical and mucoadhesive properties), and biopharmaceutical characterization of prepared mucoadhesive buccal films through conducting in vivo study in spontaneously hypertensive rats and in silico modeling of intraoral and gastrointestinal drug absorption.. For in vivo study formulation F2 (hydroxypropylmethyl cellulose 0.5%, polyethylene oxide 3.5%, polyvinyl alcohol 1.5%, propylene glycol 3%, and propranolol hydrochloride 2%) was selected, which showed the highest values of tensile strength and percentage of elongation, as well as the highest value of the force of adhesion.



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